Bought as an upgrade for ageing and failing Logitech Harmony Remote (some buttons had stopped responding).
It was dead easy to log in to the Logitech desktop app and transfer the settings over, and I was up and running in about 20 mins. Obviously, if you're starting from scratch then it's going to take a lot longer.
And yes, setting up new equipment can be a bit of pain, but that's the nature of the equipment with which we're dealing. One activity usually *does* involve switching on various devices on (and off) together, and sometimes in the right order. And no, it's not always easy to get that right. That's hardly Logitech's fault though.
The killer feature is the Hub, which use RF technology to work. Unlike infra-red, RF requires no line of sight, so if your Home Theatre is in a dedicated cupboard under the TV, like ours is, then the remote will still work when the cupboard doors are closed. With all previous remotes, we had to have one or both of the doors open to work the equipment, which was not ideal. (You may need to watch the heat that your gear generate inside that cupboard when its doors closed though.)
Docked one star for the poor battery life. The Harmony One would go weeks without a charge, but the Elite lasts only a few days. Not a biggie though. If you can remember to charge your Smart Watch and/or Smart Phone every day, then it's not too hard to remember to drop this remote in its charging cradle before you go to bed.