I've tried 3 different brands of pimple patches, out of the 3 I feel like these ones were the least effective. Still seemed to do an ok job, if anything they protected the pimple from dirt ect. I wore mine to bed and took them off in the morning, didn't completely get rid of anything, but it seemed like they slightly reduced swelling. Can only use them on pimples with a head though, won't work on cystic pimples. Stuck to the skin very well. Very cheap, but again, not the most effective. Could just be my skin though.